Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p28 | Bone biomechanics and quality | ECTS2016

Alendronate therapy improves anterior vertebral microstructure in osteoporotic bone facilitating fracture risk reduction

vom Scheidt Annika , Krause Matthias , Puschel Klaus , Amling Michael , Busse Bjorn

Although the fracture risk reduction under bisphosphonate treatment in osteoporosis is clinically well established, it remains understudied why the efficacy of bisphosphonate therapy is higher for the prevention of vertebral fractures compared to other fractures.Our aim was to investigate whether anti-resorptive therapy with alendronate would result in different regional variations of structural indices in the vertebral body. We investigated the microstr...